Two Serious Ladies: A Novel by Jane Bowles

From HarperCollins:

Two Serious Ladies is the only novel by avant-garde literary star and wife of legendary writer Paul Bowles—a modernist cult-classic, mysterious, profound, anarchic, and funny, that follows two upper-class women as they descend into debauchery—updated with an introduction by Claire Messud, bestselling author of The Emperor's Children and The Woman Upstairs.

Two serious ladies who want to live outside of themselves, Christina Goering and Frieda Copperfield embark on separate quests of salvation. Mrs. Copperfield visits Panama with her husband, where she finds solace among the women who live and work in its brothels. Miss Goering becomes involved with various men. At the end the two women meet again, each transformed by her experience.